moscot.problems.time.TemporalProblem.score_genes_for_marginals

TemporalProblem.score_genes_for_marginals(gene_set_proliferation=None, gene_set_apoptosis=None, proliferation_key='proliferation', apoptosis_key='apoptosis', **kwargs)

Compute gene scores to obtain prior knowledge about proliferation and apoptosis.

The gene scores can be used in estimate_marginals() to estimate the initial growth rates as suggested in [Schiebinger et al., 2019]

Parameters:
Return type:

BirthDeathMixin

Returns:

: Returns self and updates the following fields: